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Membrane bioreactors for hospital wastewater treatment: recent advancements in membranes and processes

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 5,   Pages 634-660 doi: 10.1007/s11705-021-2107-1

Abstract: Discharged hospital wastewater contains various pathogenic microorganisms, antibiotic groups, toxic organic compounds, radioactive elements, and ionic pollutants. These contaminants harm the environment and human health causing the spread of disease. Thus, effective treatment of hospital wastewater is an urgent task for sustainable development. Membranes, with controllable porous and nonporous structures, have been rapidly developed for molecular separations. In particular, membrane bioreactor (MBR) technology demonstrated high removal efficiency toward organic compounds and low waste sludge production. To further enhance the separation efficiency and achieve material recovery from hospital waste streams, novel concepts of MBRs and their applications are rapidly evolved through hybridizing novel membranes (non hydrophilic ultrafiltration/microfiltration) into the MBR units (hybrid MBRs) or the MBR as a pretreatment step and integrating other membrane processes as subsequent secondary purification step (integrated MBR-membrane systems). However, there is a lack of reviews on the latest advancement in MBR technologies for hospital wastewater treatment, and analysis on its major challenges and future trends. This review started with an overview of main pollutants in common hospital wastewater, followed by an understanding on the key performance indicators/criteria in MBR membranes (i.e., solute selectivity) and processes (e.g., fouling). Then, an in-depth analysis was provided into the recent development of hybrid MBR and integrated MBR-membrane system concepts, and applications correlated with wastewater sources, with a particular focus on hospital wastewaters. It is anticipated that this review will shed light on the knowledge gaps in the field, highlighting the potential contribution of hybrid MBRs and integrated MBR-membrane systems toward global epidemic prevention.

Keywords： membrane technology     membrane bioreactor     hospital wastewater     hybrid MBR     integrated MBR-membrane system    

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Formation of disinfection by-products during sodium hypochlorite cleaning of fouled membranes from membrane bioreactors

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-021-1389-3

Abstract:

•HAAs was dominant among the DBPs of interest.

Keywords： MBR     Biofouling     EPS     Chemical cleaning     DBPs     CLSM    

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Excitation-emission matrix (EEM) fluorescence spectroscopy for characterization of organic matter in membrane bioreactors

Jinlan Yu, Kang Xiao, Wenchao Xue, Yue-xiao Shen, Jihua Tan, Shuai Liang, Yanfen Wang, Xia Huang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1210-8

Abstract: • Principles and methods for fluorescence EEM are systematically outlined. • Fluorophore peak/region/component and energy information can be extracted from EEM. • EEM can fingerprint the physical/chemical/biological properties of DOM in MBRs. • EEM is useful for tracking pollutant transformation and membrane retention/fouling. • Improvements are still needed to overcome limitations for further studies. The membrane bioreactor (MBR) technology is a rising star for wastewater treatment. The pollutant elimination and membrane fouling performances of MBRs are essentially related to the dissolved organic matter (DOM) in the system. Three-dimensional excitation-emission matrix (3D-EEM) fluorescence spectroscopy, a powerful tool for the rapid and sensitive characterization of DOM, has been extensively applied in MBR studies; however, only a limited portion of the EEM fingerprinting information was utilized. This paper revisits the principles and methods of fluorescence EEM, and reviews the recent progress in applying EEM to characterize DOM in MBR studies. We systematically introduced the information extracted from EEM by considering the fluorescence peak location/intensity, wavelength regional distribution, and spectral deconvolution (giving fluorescent component loadings/scores), and discussed how to use the information to interpret the chemical compositions, physiochemical properties, biological activities, membrane retention/fouling behaviors, and migration/transformation fates of DOM in MBR systems. In addition to conventional EEM indicators, novel fluorescent parameters are summarized for potential use, including quantum yield, Stokes shift, excited energy state, and fluorescence lifetime. The current limitations of EEM-based DOM characterization are also discussed, with possible measures proposed to improve applications in MBR monitoring.

Keywords： excitation-emission matrix (EEM)     dissolved organic matter (DOM)     membrane bioreactor (MBR)     fluorescence indicator     characterization method    

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The development and application of genome editing technology in ruminants: a review

Mengke YUAN, Yuanpeng GAO, Jing HAN, Teng WU, Jingcheng ZHANG, Yongke WEI, Yong ZHANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 171-180 doi: 10.15302/J-FASE-2019302

Abstract: microinjection can offer an economic and efficient way to produce gene-edited ruminants, which can serve as bioreactors

Keywords： bioreactors     breeding     engineered endonucleases     genome editing     ruminants    

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Technological Trend and Suggestions for Cultured Meat Industry

Guan Xin, Zhou Jingwen, Du Guocheng, Chen Jian

Strategic Study of CAE 2023, Volume 25, Issue 3,   Pages 251-262 doi: 10.15302/J-SSCAE-2023.07.018

Abstract: ., biosafety cabinets and bioreactors) for cultured meat production are analyzed.

Keywords： cultured meat     seed cells     bioreactors     bioprocess of large-scale cell culture     culture medium research    

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Advanced Bioprocess Development and Manufacturing Technologies in High-Throughput Miniature Bioreactors

Jiao Peng, Chen Biqiang

Strategic Study of CAE 2016, Volume 18, Issue 4,   Pages 44-50 doi: 10.15302/J-SSCAE-2016.04.007

Abstract: technologies of ABDM include high throughput screening and process development based on micro- and mini-bioreactors

Keywords： advance bioprocess development and biomanufacturing     virulent infectious disease     precision medicine     miniature bioreactor     high throughput technology     disposable technology    

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Large-Scale Membrane Bioreactors for Industrial Wastewater Treatment in China: Technical and Economic Review

Jiao Zhang, Kang Xiao, Ziwei Liu, Tingwei Gao, Shuai Liang, Xia Huang

Engineering 2021, Volume 7, Issue 6,   Pages 868-880 doi: 10.1016/j.eng.2020.09.012

Abstract:

Membrane bioreactors (MBRs) have been and will continue playing an important role in industrial wastewater

Keywords： Full-scale application     Treatment capacity     Parameter     Footprint     Geographic demand     Policy    

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Global Significance of Substrates for Nitrate Removal in Denitrifying Bioreactors Revealed by Meta-Analysis Review

Yuchuan Fan, Jie Zhuang, Michael Essington, Sindhu Jagadamma, John Schwartz, Jaehoon Lee

Engineering 2023, Volume 21, Issue 2,   Pages 214-226 doi: 10.1016/j.eng.2022.08.017

Abstract:

Denitrifying bioreactors (DNBRs) are widely used to reduce excess nitrate

Keywords： Denitrifying bioreactor     Substrate     Nitrate removal     Meta-analysis     Environmental impact     Cost analysis    

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Title Author Date Type Operation

Membrane bioreactors for hospital wastewater treatment: recent advancements in membranes and processes

Journal Article

Formation of disinfection by-products during sodium hypochlorite cleaning of fouled membranes from membrane bioreactors

Journal Article

Excitation-emission matrix (EEM) fluorescence spectroscopy for characterization of organic matter in membrane bioreactors

Jinlan Yu, Kang Xiao, Wenchao Xue, Yue-xiao Shen, Jihua Tan, Shuai Liang, Yanfen Wang, Xia Huang

Journal Article

The development and application of genome editing technology in ruminants: a review

Mengke YUAN, Yuanpeng GAO, Jing HAN, Teng WU, Jingcheng ZHANG, Yongke WEI, Yong ZHANG

Journal Article

Technological Trend and Suggestions for Cultured Meat Industry

Guan Xin, Zhou Jingwen, Du Guocheng, Chen Jian

Journal Article

Advanced Bioprocess Development and Manufacturing Technologies in High-Throughput Miniature Bioreactors

Jiao Peng, Chen Biqiang

Journal Article

Large-Scale Membrane Bioreactors for Industrial Wastewater Treatment in China: Technical and Economic

Jiao Zhang, Kang Xiao, Ziwei Liu, Tingwei Gao, Shuai Liang, Xia Huang

Journal Article

Global Significance of Substrates for Nitrate Removal in Denitrifying Bioreactors Revealed by Meta-Analysis

Yuchuan Fan, Jie Zhuang, Michael Essington, Sindhu Jagadamma, John Schwartz, Jaehoon Lee

Journal Article